Researchers Use AI to Design Enzymes That Cut Specific Proteins

Researchers used AI-based protein design tools to create enzymes tuned to cut specific proteins in half, demonstrating their effectiveness on proteins associated with neurological diseases. The researchers started with two types of protease—enzymes that cut other proteins—and retained each type’s catalytic core while replacing the rest of the protein. This approach let them change which proteins the enzymes targeted while preserving the machinery that performs the cutting.

Generated by AI from reports · Updated 2 days ago