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Claude Sonnet 5 Selected and Administered Gene Therapy in a Supervised Mouse Experiment

1 reports 1 reporting sources 1 hours agoNew

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Exin Therapeutics cofounder Gabriel Ocana-Santero reported that his team used Claude Sonnet 5 to select a gene therapy, brain target and injection parameters, then control a surgical device to treat a mouse model of epilepsy. Ocana-Santero said the mouse recovered well, but that does not establish whether the treatment worked; the results have not been peer-reviewed. A licensed veterinarian approved every irreversible step and held a physical emergency stop that could cut power to all motors. The setup also imposed fixed limits, including an injection-volume cap the agent was forbidden from bypassing. During surgery, the agent correctly detected a device range problem and refused to proceed until Ocana-Santero manually fixed the code.

Generated by AI from reports · Updated 1 hours ago

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10/31
  1. Claude Sonnet 5 selected and administered gene therapy in a mouse experiment

    Gabriel Ocana-Santero reports that Claude Sonnet 5 selected a gene therapy, brain target, and injection parameters, then controlled a surgical device to treat an epilepsy mouse model. A licensed veterinarian approved every irreversible step and held a physical emergency stop. During surgery, the agent correctly detected a device range problem and refused to proceed until Ocana-Santero fixed the code manually. He says the mouse recovered well; treatment efficacy was not reported, a technical report is expected, and the results have not been peer-reviewed.

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