- Who
- Google DeepMind
- What
- unveils AlphaGenome 2, an AI model that predicts genetic variant effects across individual cell types and states
- Quote
AlphaGenome 2 is our new AI model that zooms in on specific cells to help scientists understand what drives disease.
Read next
See the full storyGoogle DeepMind Releases AlphaGenome 2 for Cell-Specific Genetic ResearchReported by 6 sources
Your heart, brain, and immune system share the same DNA sequence. So how can a single-letter change affect disease in some cells, while sparing the rest?
AlphaGenome 2 is our new AI model that zooms in on specific cells to help scientists understand what drives disease. 🧵
The story so far
Google DeepMind has released AlphaGenome 2, a model that predicts how DNA variants affect specific human cell types and states. The model is available through the AlphaGenome API for non-commercial research, while commercial research access is in a closed private preview. Google says it is intended for research and has not been validated or approved for clinical or diagnostic use. Google says AlphaGenome 2 was trained on more than 107 million cell profiles. On the TenK10K benchmark, it identified nearly twice as many causal variants as the original AlphaGenome; The Decoder reports about 30 percent for AlphaGenome 2 versus 16 percent for a fine-tuned AlphaGenome 1.
How the story developed · 2
View full event- 11/12 00:02 (UTC+8)
Your heart, brain, and immune system share the same DNA sequence. So how can a single-letter change affect disease in some cells, while sparing the rest? AlphaGenome 2 is our new AI model that zooms in on specific cells to help scientists understand what drives disease. 🧵 This report
- 11/11 23:20 (UTC+8)Google DeepMind Announces AlphaGenome 2 for Cell-Specific DNA Variant PredictionGoogle DeepMind

