Ian Quigley Explains Leash Bio’s Data Methods and Lab-in-the-Loop Agent Research
Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio
What happened
Brandon Anderson interviews Leash Bio’s Ian Quigley about generating reproducible protein–small molecule interaction data using DNA Encoded Libraries and detecting misleading signals in experiments and models. They discuss a Kaggle competition with about 4B measurements where nobody beat chance on an unseen chemical library, and an agent sandbox searching 6.5M molecules on a budget of 100. Anderson reports that the sandbox has matured into Minos, with a preprint, blog, and open dataset being released today.
Keep reading
Latest daily · Issue 24NVIDIA and AI4Bharat Introduce Nemotron-pretraining-Indic-v1 and an Open Data Generation PipelineTrending now
- 1Meta Releases Muse Spark Open With Mac and Cloud Support, Topping US Open-Weight Index
- 2Google Launches Gemini 4 Argon Globally, Expands Paid Access as Benchmark Results Vary
- 3OpenAI Updates GPT-6 Astra Pro in ChatGPT With Parallel Agents and Faster Responses
- 4Meta’s New Business Terms Raise Dispute Over Website Crawling and AI Training Rights
Tomorrow at 08:00, a briefing like this arrives in your inbox.
The same kind of briefing as the one above: a few stories worth reading. Free. Mail starts after you confirm, and every letter has a one-click unsubscribe. Read a past issue · 2026-10-17